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Medchemexpress LLC Pmx-53 (Ac-Phe-Orn-Pro-dCha-Trp-Arg; lactam bridge Orn2-Arg6) | 219639-75-5 | 896.09 | C47H65N11O7 | 5 MG
SDP

Supplier:  Medchemexpress LLC HY1061785MG

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PMX-53 is a synthetic cyclic peptidic antagonist of the complement C5a receptor (C5aR1) used in research on immunology and inflammation. It is orally active and shows potent receptor inhibition (IC50 ≈ 20 nM). Chemical identifiers include CAS 219639-75-5 and molecular weight 896.09; sequence: Ac-Phe-{Orn}-Pro-{dCha}-Trp-Arg (lactam bridge Orn2-Arg6).

  • Orally active C5a receptor antagonist with potent in vitro activity.
  • Applicable to studies of complement-mediated inflammation, cancer, and atherosclerosis.
  • Cyclic peptidic structure with a defined sequence and lactam bridge for stability.
  • High solubility in DMSO and water for in vitro preparation.
  • Stable under sealed, low-temperature storage; specific solvent storage lifetimes provided.

Catalog No. 50-002-42674


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