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BEZWADA BIOMEDICAL LLC Poly(glycolide), viscosity 1.0 to 2.0 dl/g, 5.0 GM
Supplier: BEZWADA BIOMEDICAL LLC 2100
Polyglycolide is prepared by the ring-opening polymerization of glycolide monomer. Ring opening polymerization provides high-molecular weight polyglycolide, the simplest linear aliphatic polyester. Polyglycolide was originally used to manufacture the first totally synthetic absorbable suture, marketed as DexonTM in the 1970s by Davis and Geck, Inc. The high crystallinity of PGA (40-55%) limits its solubility in most organic solvents with the exception of highly fluorinated organic solvents such as hexafluoroisopropanol and hexafluoroacetone. PGA exhibits a high melting point (220-225°C) and a glass-transition temperature of 35-40°C. Although fibers from PGA exhibit high tensile strength and modulus, they are too stiff to be used as sutures except in the form of braided material. A typical suture braid prepared from PGA loses about 50% of its strength after 2 weeks and 100% at 4 weeks, and is completely absorbed in 3-4 months.
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