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Cayman Chemical PolygalasponIn F 10mg

Supplier: Cayman Chemical 3006410 MG
A triterpenoid saponin with diverse biological activities; inhibits LPS-induced increases in TNF-α and NO production, iNOS levels, and nuclear translocation of NF-κB p65 in BV-2 microglia at 0.1, 1, and 10 μM; inhibits rotenone-induced increases in intracellular ROS levels, decreases in mitochondrial membrane potential, and induction of apoptosis in PC12 cells at 0.1, 1, and 10 μM; intracerebroventricular administration induces long-term potentiation in the hippocampal dentate gyrus in anesthetized rats at 1 and 10 μM, an effect that can be prevented by MK-801 or KN-93
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