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Medchemexpress LLC Pramipexole dihydrochloride hydrate | 191217-81-9 | 98.0% | 1 ML

Supplier: Medchemexpress LLC HYB0410A10MM/1ML
Pramipexole dihydrochloride hydrate is a selective and blood-brain barrier (BBB) penetrant dopamine D2-type receptor agonist, with Kis of 2.2 nM, 3.9 nM, 0.5 nM, and 1.3 nM for D2-type receptor, D2, D3, and D4 receptors, respectively. It can be used for the research of Parkinson's disease (PD) and restless legs syndrome (RLS).
- Selective and blood-brain barrier penetrant dopamine D2-type receptor agonist
- Used for research of Parkinson's disease (PD) and restless legs syndrome (RLS)
- Shows low binding affinity for D1-type receptor (>50,000 nM IC50)
- Attenuates levodopa-induced toxicity in mesencephalic cultures
- Significantly reduces infarction volume and improves neurological recovery
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