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Cayman Chemical Precellys Evolution Touch Ex
SDP

Supplier:  Cayman Chemical 387111 EA

Encompass

An active metabolite of quetiapine selectively inhibits NET (IC50 12 nM) over SERT and DAT (IC50s 988 and 10000 nM respectively) binds to the histamine H1 receptor (Ki 3.5 nM) as well as 5-HT1 5-HT2 and 5-HT7 a1- and a2-adrenergic dopamine D1-D5 and M1-M5 muscarinic receptors (Kis 45-1117 nM 95-736 196-1419 and 23-453 nM respectively) an antagonist at histamine H1 a1A- and a1D-adrenergic M1 M3 and M5 muscarinic receptors in a concentration-dependent manner and an agonist at the 5-HT1A receptor (EC50 4898 nM) reduces increases in immobility time in Vmat2 heterozygous mice at 0.1 0.5 and 1 mg/kg

Catalog No. 50-291-6485


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