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Cayman Chemical Precelys MInIlys - Fuse 1ea
SDP

Supplier:  Cayman Chemical 387261 EA

Encompass

An inhibitor of SIK2 (IC50 0.04 UM for the human enzyme) selective for SIK2 over a panel of 141 kinases at 1 UM but also inhibits 14 other kinases including SIK3 Ephrin receptors and Src increases IL-10 production in zymosan A-induced isolated mouse BMDCs (EC50 0.46 UM) decreases TNF-a IL-6 and IL-12p40 levels and increases IL-1B levels in LPS-stimulated BMDCs at 1 UM inhibits the proliferation of MOLM-13 cells (IC50 0.24 UM) increases the bone formation rate and number of femoral osteoblasts and decreases the number of femoral osteoclasts in mice at 10 Umol/kg

Catalog No. 50-291-6516


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