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Cayman Chemical PrecoatedGoat ntI-Mouse Ig 1ea
Supplier: Cayman Chemical 4000091 EA
An ionizable cationic lipid has been used in the generation of lipid nanoparticles for the delivery of mRNA in vitro or in vivo LNPs containing C14-4 and encapsulating mRNA encoding CAR induce CAR expression in primary human T cells ex vivo to the same level as expression induced via electroporation but with reduced cytotoxicity and induce cytotoxicity in Nalm-6 ALL cells in vitro LNPs containing C14-4 and deoxycholic acid and encapsulating mRNA encoding luciferase accumulate in the uterus when intraperitoneally administered and in the lungs and small intestine when intravenously administered in mice
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