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Abcam PRIMA-1MET, p53 activity, 10MG
Supplier: Abcam AB14597410MG
MW 199.25 Da, Purity >98%. Methylated derivative of PRIMA-1 (ab141641). Restores wild-type conformation and function to mutant p53, and triggers apoptosis in tumor cells. Acts synergistically with chemotherapeutic agents to inhibit tumor cell proliferation. Inhibits thioredoxin reductase 1 (TrxR1), a key regulator of cellular redox balance.
The product is subject to the following: Abcam Restricted Use Statement
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