Biotium Primary Antibody Beta catenin Catenin Beta PAb CF740 1/EA

Supplier:  Biotium BNC740376500

Beta-catenin associates with the cytoplasmic portion of E-cadherin The catenin/cadherin complexes play an important role mediating cellular adhesion including adherens junctions Beta-catenin is involved in the Wnt signaling pathway as well as other signaling pathways and is also found in complexes with many different proteins including the tumor suppressor protein APC Defects in beta-catenin are associated with colorectal cancer as well as many other cancer types Beta-catenin is normally localized to the cell membrane but can translocate to the nucleus in response to certain cell signaling Primary antibodies are available purified or with a selection of fluorescent CF Dyes and other labels CF Dyes offer exceptional brightness and photostability Note Conjugates of blue fluorescent dyes like CF405S and CF405M are not recommended for detecting low abundance targets because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors

Catalog No. 50-004-99243