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Biotium Primary Antibody MART 1 Melan A M2-7C10 CF740 1/EA
Supplier: Biotium BNC740009100
This antibody recognizes a protein doublet of 20-22 kDa identified as MART-1 (Melanoma Antigen Recognized by T cells 1) or Melan-A MART-1 is a newly identified melanocyte differentiation antigen recognized by autologous cytotoxic T lymphocytes Seven other melanoma associated antigens recognized by autologous cytotoxic T cells include MAGE-1 MAGE-3 tyrosinase gp100 gp75 BAGE-1 and GAGE-1 Subcellular fractionation shows that MART-1 is present in melanosomes and endoplasmic reticulum This MAb labels melanomas and other tumors showing melanocytic differentiation It is also a useful positive-marker for angiomyolipomas It does not stain tumor cells of epithelial lymphoid glial or mesenchymal origin Primary antibodies are available purified or with a selection of fluorescent CF Dyes and other labels CF Dyes offer exceptional brightness and photostability Note Conjugates of blue fluorescent dyes like CF405S and CF405M are not recommended for detecting low abundance targets because blue dyes
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