Medchemexpress LLC Propargyl-PEG4-CH2COOH | 1429934-37-1 | >=97.0% | 290.31 | 50 MG

Supplier:  Medchemexpress LLC HY14002350MG

Propargyl-PEG4-CH2COOH is a PEG-based PROTAC linker utilized in the synthesis of PROTACs. It functions as a click chemistry reagent, containing an Alkyne group that facilitates copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules possessing Azide groups. PROTACs themselves consist of two different ligands connected by a linker; one ligand targets an E3 ubiquitin ligase, and the other targets the protein of interest, enabling selective degradation of target proteins via the intracellular ubiquitin-proteasome system.

• PEG-based PROTAC linker
• Used in the synthesis of PROTACs
• Functions as a click chemistry reagent
• Contains an Alkyne group
• Facilitates copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules possessing Azide groups
• Enables selective degradation of target proteins

Catalog No. 50-003-50302