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Medchemexpress LLC Protac Bcl2 degrader-1 | 2378801-85-3 | 99.8% | 941.84 g/mol | C45H45BrN6O10S | 10MG
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Supplier:  Medchemexpress LLC HY12587610MG

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PROTAC Bcl2 degrader-1 is a cereblon-based proteolysis targeting chimera designed to selectively induce degradation of Bcl-2 and to show activity against Mcl-1. It is intended for biochemical and cellular research, supplied as a light yellow to yellow solid with high chemical purity and characterized potency in degradation assays.

  • Induces degradation of Bcl-2 and shows activity against Mcl-1.
  • Reported Bcl-2 IC50 4.94 μM and DC50 3.0 μM.
  • High chemical purity of 99.8%.
  • Molecular weight approximately 941.8 g/mol.
  • Supplied as a light yellow to yellow solid for research use.
  • Recommended storage at -20°C under inert gas; solvent stability and handling details available in technical documents.

Catalog No. 50-002-35026


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