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Medchemexpress LLC Protac EED degrader-1 | 2639882-72-5 | 98.3% | C55H60FN11O8S | 10MG
Supplier: Medchemexpress LLC HY13061410MG
PROTAC EED degrader-1 is a von Hippel-Lindau (VHL)-based proteolysis targeting chimera designed to bind and induce degradation of EED, a subunit of the polycomb repressive complex 2 (PRC2). It exhibits potent biochemical and cellular activity, leads to downregulation of EZH2 and H3K27me3, and has shown cellular apoptosis and antitumor effects in preclinical models.
- Potent EED-targeting degrader with low nanomolar biochemical activity.
- Reduces EZH2 protein levels and decreases H3K27me3 in cells.
- Induces apoptosis and shows antitumor activity in preclinical models.
- High reported purity for research applications.
- Available in multiple small-scale quantities for laboratory studies.
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