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Medchemexpress LLC Protac EGFR degrader 4 | 2882845-50-1 | 99.7% | 995.29 | C55H70N12O4S | 5 MG
Supplier: Medchemexpress LLC HY1463495MG
PROTAC designed to selectively target and induce degradation of mutant forms of the epidermal growth factor receptor (EGFR). Demonstrates potent degradation of EGFRdel19 and EGFRL858R/T790M in cellular assays and inhibits growth of EGFR-driven cancer cell lines. Supplied as a high-purity research reagent with recommended solvent and storage conditions.
- Targets mutant EGFR, inducing degradation of activating and resistance variants.
- Demonstrated cellular potency with low-nanomolar DC50 values.
- High reported purity suitable for biochemical and cellular studies.
- Soluble in DMSO at 100 mg/mL; may require ultrasonic treatment.
- Store protected from light and under inert atmosphere; in solvent: -80°C (6 months), -20°C (1 month).
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