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Medchemexpress LLC PROTAC ERRα Degrader-3 | 2306388-65-6 | 98.7% | 956.99 | 100 MG
Supplier: Medchemexpress LLC HY139185100MG
PROTAC ERRα Degrader-3 is a potent and selective ERRα degrader based on von Hippel-Lindau ligand. It is capable of specifically degrading ERRα protein by >80% at a concentration of 30 nM and is inactive against ERRβ and ERRγ proteins. It is for research use only.
- Potent and selective ERRα degrader
- Dose-dependently induces ERRα degradation
- Decreases protein levels of ERRα downstream target genes (ATP5B, MCAD, PDK4)
- Blocks protein-protein interaction of ERRα with PGC-1α peptide
- Induces approximately 96% protein degradation at 100 nM
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