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Medchemexpress LLC PROTAC HSP90 degrade 100mg | 2669072-88-0 | 641.08 | C32H29ClN8O5 | 100 MG
Supplier: Medchemexpress LLC HY115997100MG
PROTAC HSP90 degrader BP3 is a research-grade PROTAC that induces CRBN-dependent degradation of heat shock protein 90 (HSP90). It shows potent cellular activity (DC50 ≈ 0.99 μM in MCF-7 cells), inhibits growth of several breast cancer cell lines in vitro, and demonstrated tumor growth inhibition in animal studies. Supplied as a solid and as a 10 mM solution in DMSO for laboratory research use only.
- Crbn-dependent HSP90 degradation with DC50 ≈ 0.99 μM in MCF-7 cells.
- Inhibits growth of multiple breast cancer cell lines in vitro.
- Available as solid (5 mg-100 mg) and as 10 mM solution in DMSO.
- High reported purity (~99.5%) with supporting COA, LC-MS, and NMR data.
- Storage recommendations: powder -20°C (long term) and solution -80°C (long term).
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