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Medchemexpress LLC Protopine | 130-86-9 | 353.37 | 50 MG
Supplier: Medchemexpress LLC HYN079350MG
Protopine (Corydinine) is an isoquinoline alkaloid that acts as a specific reversible and competitive inhibitor of acetylcholinesterase. It exhibits anti-inflammatory, anti-microbial, anti-angiogenic, and anti-tumor activities.
- Inhibits cell viability, migration, invasion, and EMT process in liver carcinoma cells.
- Induces apoptosis by increasing caspase-3 and caspase-9 expression.
- Inhibits the PI3K/Akt signaling pathway.
- Induces ROS generation.
- Inhibits the uptake of serotonin transporter (SERT) and noradrenaline (NE).
- Alleviates scopolamine-induced memory impairment.
- Inhibits tumor growth in xenograft mice.
- Shows antidepressant-like effects.
- Exhibits protective effects on focal cerebral ischemic injury.
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