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Medchemexpress LLC Protoporphyrin IX | 553-12-8 | MFCD00078028 | ≥98.0% | 100 MG
SDP

Supplier:  Medchemexpress LLC HYB1247100MG

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Protoporphyrin IX is a final intermediate in the heme biosynthetic pathway, which acts as a radiation sensitizer enhancing ROS generation even in a hypoxic state and inducing DNA damage. It also functions as a photosensitizer, undergoing photobleaching through direct degradation by light irradiation. It accumulates following 5-aminolevulinic acid (5-ALA) administration in rat tumor cells. When activated by red fluorescence at a peak wavelength of 405 nm, Protoporphyrin IX selectively improves basal cell carcinoma. It shows promise as a sonodynamic and photodynamic agent for various cancers, including bladder cancer and nodular basal cell carcinoma.

  • Acts as a radiation sensitizer enhancing ROS generation.
  • Induces DNA damage.
  • Acts as a photo sensitizer.
  • Promising for research of sonodynamic and photodynamic agents for a wide range of cancers.

Catalog No. 50-004-11846


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