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Medchemexpress LLC Protoporphyrin IX (disodium) | 50865-01-5 | 96.5% | 25 MG

Supplier: Medchemexpress LLC 25MGHYB1247A
Protoporphyrin IX disodium is a final intermediate in the heme biosynthetic pathway. It acts as a radiation sensitizer, enhancing ROS generation even in hypoxic conditions and inducing DNA damage. It also functions as a photosensitizer, undergoing photobleaching through direct degradation by light irradiation. This product is promising for research of sonodynamic and photodynamic agents for various cancers, including bladder cancer and nodular basal cell carcinoma.
- Final intermediate in the heme biosynthetic pathway
- Acts as a radiation sensitizer
- Enhances ROS generation and induces DNA damage
- Functions as a photosensitizer
- Undergoes photobleaching by light irradiation
- Accumulates in tumor cells after 5-aminolevulinic acid administration
- Causes selective improvement of basal cell carcinoma
- Promising for research into sonodynamic and photodynamic agents for various cancers
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