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Selleck Chemical LLC Purvalanol A

Supplier: Selleck Chemical LLC S7793100MG
Purvalanol A is a potent and cell-permeable CDK inhibitor with IC50 of 4 nM 70 nM 35 nM and 850 nM for cdc2-cyclin B cdk2-cyclin A cdk2-cyclin E and cdk4-cyclin D1 respectively Purvalanol A induces endoplasmic reticulum stress-mediated apoptosis and autophagy
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