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Bachem (Pyr3)-Amyloid Beta Protein (3-42) Ammonium

Supplier: Bachem 4029424.0500

(Pyr3)-Amyloid Beta Protein (3-42) Ammonium, Pyr-Phe-Arg-His-Asp-Ser-Gly-Tyr-Glu-Val-His-His-Gln-Lys-Leu-Val-Phe-Phe-Ala-Glu-Asp-Val-Gly-Ser-Asn-Lys-Gly-Ala-Ile-Ile-Gly-Leu-Met-Val-Gly-Gly-Val-Val-Ile-Ala-OH, 183449-57-2, C196H299N53O55S, Mr 4309.92, 0.5mg. (Glp3) b-Amyloid (3-42). (Pyr3)-Amyloid b-Protein (3-42) was found to be the predominant amyloid b-peptide structure deposited in human brain of Alzheimer's disease and Down's syndrome patients. Therefore, (Pyr3)-Ab (3-42) is suggested to accumulate in the brain and to trigger the formation of insoluble amyloid b-peptide deposits. Nussbaum et al. studies the Prion-like behaviour and tau-dependent cytotoxicity of the truncated Ab sequence.
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