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Enzo Life Sciences QS11 (25 mg). CAS: 944328-88-5
SDP

Supplier:  Enzo Life Sciences BMLWN1170025

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Synergizers with Wnt3a to activate the Wnt/β-catenin pathway. Binds and inhibits GTPase activating protein of ADP-ribosylation factor 1 (ARFGAP1), thus activating ARF. It has also been suggested that a possible mechanism by which QS11 synergizes Wnt is through ARFGAP1 inhibition leading to increased β-catenin translocation via ARF activation. Alternative name: (2S)-2-[2-(Indan-5-yloxy)-9-(1,1'-biphenyl-4-ylmethyl)-9H-purin-6-ylamino]-3-phenyl-propan-1-ol. Purity: ≥98% (HPLC). Solubility: Soluble in DMSO (25 mg/ml) or in 100% ethanol (25 mg/ml). Long Term Storage: -20°C.

Catalog No. 50-201-2374


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