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Cayman Chemical QuInaprIlat 10mg
Supplier: Cayman Chemical 3600710 MG
An ACE inhibitor (IC50 = 0.06 nM) and active metabolite of quinapril; inhibits LPC-induced calcium overload and rod to round cell shape change in isolated rat cardiomyocytes at 20 and 50 µM; reduces the frequency of ventricular fibrillation in a dog model of myocardial ischemia and reperfusion injury at 3 UG/kg; reduces blood pressure and proteinuria in rat models of uranyl nitrate- or 5/6 nephrectomy-induced chronic renal failure at 0.1 mg/kg
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