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Medchemexpress LLC Quinoline val-asp difluorophenoxymethylketone | 1135695-98-5 | MFCD08669741 | 99.9% | 513.49 g/mol | C26H25F2N3O6 | 100MG
Supplier: Medchemexpress LLC HY12305100MG
Q-VD-OPh is an irreversible, cell-permeable pan-caspase inhibitor used to block caspase-dependent apoptosis in biochemical and cell-based assays. It inhibits caspase-7 with an IC50 of 48 nM and shows activity against caspases 1, 3, 8, 9, 10, and 12 in the 25-400 nM range. Reported properties include low cytotoxicity and the ability to cross the blood-brain barrier.
- Potent pan-caspase inhibition with low nanomolar activity.
- Cell permeable for use in live-cell assays.
- Low intrinsic cytotoxicity in standard assays.
- Capable of crossing the blood-brain barrier.
- High chemical purity suitable for research applications.
- Supplied as a solid powder for convenient storage and handling.
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