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Medchemexpress LLC (R)-1-(7-chloro-2,2-bis(fluoromethyl)chroman-4-yl)-3-(3-methylisoquinolin-5-yl)urea | 1221443-94-2 | 99.9% | 431.86 | C22H20ClF2N3O2 | 10MM 1ML
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Supplier:  Medchemexpress LLC HY1242810MM 1ML

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A-1165442 is a potent, temperature-neutral TRPV1 antagonist described in the medicinal chemistry literature and used for preclinical analgesia research. It exhibits high potency against human TRPV1 and is supplied as a ready-to-use 10 mM solution in DMSO intended for in vitro and pharmacology studies.

  • Potent TRPV1 antagonism (IC50 ≈ 9 nM for human TRPV1).
  • Temperature-neutral profile with demonstrated analgesic efficacy in preclinical models.
  • Supplied as 10 mM solution in DMSO, 1 mL vial, ready for use.
  • Vendor-reported purity 99.92%.
  • Molecular weight 431.86 g/mol; formula C22H20ClF2N3O2.
  • Recommended storage: powder -20°C; in solvent -80°C for long-term stability.
  • For research use only; not for human or clinical use.

Catalog No. 50-002-37891


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