Medchemexpress LLC (R)-eIF4A3-IN-2 | 2095484-82-3 | 602.70 | 50 MG

Supplier:  Medchemexpress LLC HY4391350MG

(R)-eIF4A3-IN-2 is a less active enantiomer of eIF4A3-IN-2. It is a highly selective and noncompetitive eukaryotic initiation factor 4A-3 (eIF4A3) inhibitor with an IC50 of 110 nM. This compound targets eukaryotic initiation factor (eIF) and is involved in the cell cycle/DNA damage pathway.

• Targets eukaryotic initiation factor (eIF)
• Involved in cell cycle/DNA damage pathway
• Powder storage: -20°C for 3 years, 4°C for 2 years
• In solvent storage: -80°C for 2 years, -20°C for 1 year
• Solubility in DMSO: 50 mg/mL (need ultrasonic)
• In vivo solubility: ≥ 2.5 mg/mL in 10% DMSO >> 40% PEG300 >> 5% Tween-80 >> 45% saline
• In vivo solubility: ≥ 2.5 mg/mL in 10% DMSO >> 90% corn oil

Catalog No. 50-004-03886