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Medchemexpress LLC (R)-Naproxen | 23979-41-1 | C14H14O3 | 100 MG
Supplier: Medchemexpress LLC HY15031100MG
l-Naproxen ((R)-Naproxen) is an enantiomer of (S)-Naproxen. It can inhibit Cdc42 and Rac1 with EC50 values of 96 μM and 212 μM, respectively, and exhibits anti-tumor activity. l-Naproxen is also a nonsteroidal anti-inflammatory agent (NSAID). In HeLa cells, l-Naproxen selectively inhibits Rac1 and Cdc42 activity in a dose-dependent manner. It also inhibits the migration of immortalized human ovarian cancer cells and demonstrates activity through a COX-independent mechanism.
- Inhibits Cdc42 and Rac1 with EC50 values of 96 μM and 212 μM
- Demonstrates anti-tumor activity
- Acts as a nonsteroidal anti-inflammatory agent (NSAID)
- Selectively inhibits Rac1 and Cdc42 activity in HeLa cells
- Inhibits migration of immortalized human ovarian cancer cells
- Shows activity via a COX-independent mechanism
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