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Enzo Life Sciences (R)-Roscovitine (5mg). CAS: 186692-46-6

Supplier: Enzo Life Sciences BMLCC2050005

Potent and selective inhibitor of CDKs. Selective for CDK1/cyclin B kinase (IC50=450nM) [2], CDK2 (IC50=700nM) [4] and CDK5/p35 (IC50=160nM) [4,5]. More potent than olomoucine (BML-CC200). Inhibits M phase promoting factor (MPF) kinase activity. Has effects on calcium channel gating. Alternative name: 6-Benzylamino-2-(R)-[(1-ethyl)-2-hydroxyethylamino]-9-isopropylpurine, 2(R)-(1-Ethyl-2-hydroxyethylamino)-6-benzylamino-9-isopropylpurine, Seliciclib. Purity: ≥95% (HPLC, TLC). Solubility: Soluble in DMSO. Long Term Storage: -20°C.
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