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Medchemexpress LLC (Rac)-JBJ-04-125-02 acetate | 00-00-0 | MFCD32709390; MFCD16606534 | 98.7% | 543.61 g/mol | C29H26FN5O3S | 5 MG
Supplier: Medchemexpress LLC HY135805B5MG
(Rac)-JBJ-04-125-02 acetate is the racemic acetate salt of a research-grade allosteric EGFR inhibitor. It is a potent, mutant-selective, orally active compound with reported sub-nanomolar biochemical potency against the L858R/T790M EGFR variant and demonstrated single-agent activity in cellular and animal models. Supplied as a white to off-white solid for laboratory research use only.
- Potent, mutant-selective EGFR inhibition with sub-nanomolar biochemical potency.
- Demonstrated single-agent activity in both in vitro and in vivo models.
- Allosteric mode of action complementary to ATP-site inhibitors.
- Available as a racemic acetate solid suitable for assay and formulation work.
- Provided with documentation such as COA, HPLC, and NMR upon request.
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