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Medchemexpress LLC Rac-XL177A | 2417089-73-5 | 861.47 | C48H57ClN8O5 | 5 MG
Supplier: Medchemexpress LLC HY138794A5MG
(Rac)-XL177A is the racemic isomer of XL177A, a highly potent and selective irreversible inhibitor of the deubiquitinase USP7. It exhibits sub-nanomolar biochemical potency (reported IC50 ~0.34 nM) and elicits cancer cell-killing effects predominantly through a p53-dependent mechanism, making it suitable for biochemical and cell-based research into USP7 and p53 pathways.
- Racemic small molecule USP7 inhibitor with sub-nanomolar potency.
- Irreversible mechanism of action for sustained target engagement.
- Induces p53-dependent cancer cell killing in cellular assays.
- Suitable for biochemical and cell-based studies probing deubiquitinase function.
- Available in multiple vial sizes for screening and follow-up studies.
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