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Medchemexpress LLC Radiprodil | 496054-87-6 | 99.16% | 397.40 | 50 MG
SDP

Supplier:  Medchemexpress LLC HY1477750MG

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Radiprodil is an orally active and selective NMDA NR2B antagonist. It is considered a potential therapeutic agent for the treatment of neuropathic pain and possibly other chronic pain conditions.

  • Orally active and selective NMDA NR2B antagonist.
  • Potential therapeutic agent for neuropathic pain and other chronic pain conditions.
  • Has been shown to restore long-term potentiation (LTP) in the presence of certain amyloid-beta species (Aβ1-42, 3NTyr10-Aβ, and Aβ1-40) at 10 nM.
  • Reverses the synaptic toxicity of 3NTyr-AβAβ1-40 and Aβ1-42.
  • Can block NMDA currents in Mg2+ insensitive variants, with higher potency at pH 7.0 than at pH 7.6.

Catalog No. 50-003-62830


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