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Selleck Chemical LLC RAF709 5mg 1628838-42-5

Supplier: Selleck Chemical LLC S86905MG

RAF709 is a potent inhibitor of B/C RAF kinase with almost equivalent IC50 values of 0.4 nM for B-RAF and C-RAF, showing a high level of selectivity, demonstrating greater than 99% on-target binding to BRAF, BRAFV600E, and CRAF at 1 ?M and very few off-targets with DDR1 (>99%), DDR2 (86%), FRK (92%), and PDGFRb (96%), the only kinases with binding >80% at 1 ?M. *For Research & Development use only. Product is not intended for drug, household, or human consumption.
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