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Apexbio Technology LLC Raloxifene HCl 82640-04-8 100mg
Supplier: Apexbio Technology LLC B1515100
Raloxifene HCl (82640-04-8) is a selective estrogen receptor (ER) modulator targeting estrogen receptors and human liver cytosolic aldehyde oxidase It is designed to modulate ER and aldehyde oxidase activities thereby regulating estrogen signaling and oxidative metabolic pathways Raloxifene HCl exerts its biological activity primarily through noncompetitive inhibition of estrogen receptors and aldehyde oxidase-mediated reactions In in vitro studies Raloxifene HCl demonstrates inhibitory activity on human liver cytosolic aldehyde oxidase with IC50 values ranging from 2 9 to 5 7 nM and Ki values of 0 87 1 4 nM for oxidative reactions and 52 nM for reduction reactions Based on these pharmacological properties Raloxifene HCl holds research potential in investigating ER signaling pathways enzyme inhibition and metabolic processes in vitro
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