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Selleck Chemical LLCSupplier Diversity Partner Raltegravir (MK-0518) 5mg 518048-05-0  DFS Item

Manufacturer:  Selleck Chemical LLCSupplier Diversity Partner S20055MG

Raltegravir (MK-0518) is a potent integrase (IN) inhibitor for WT and S217Q PFV IN with IC50 of 90 nM and 40 nM in cell-free assays, respectively. It shows greater than 1000-fold selectivity for HIV-1 IN over several related Mg2+-dependent enzyme such as HCV polymerase, HIV reverse transcriptase, HIV RNaseH and human α-, β-, γ-polymerases.

Catalog No. 50-615-0


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