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Medchemexpress LLC Rasarfin | 674359-73-0 | 99.57% | 425.91 | 100 MG

Supplier: Medchemexpress LLC HY139950100MG
Rasarfin is a dual Ras and ARF6 inhibitor.
- Potently inhibits agonist-induced ERK1/2 signaling by GPCRs, and MAPK and Akt signaling by EGFR.
- Prevents cancer cell proliferation.
- Blocks GPCR internalization through inhibition of ARF6.
- Treatment results in a dose-dependent reduction in MDA-MB-231 cells.
- Inhibits the recruitment of the clathrin adaptor AP-2 to β-arrestin2 and receptor internalization, both processes that require active ARF6.
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