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Medchemexpress LLC Rasarfin | 674359-73-0 | 99.57% | 425.91 | 100 MG
SDP

Supplier:  Medchemexpress LLC HY139950100MG

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Rasarfin is a dual Ras and ARF6 inhibitor.

  • Potently inhibits agonist-induced ERK1/2 signaling by GPCRs, and MAPK and Akt signaling by EGFR.
  • Prevents cancer cell proliferation.
  • Blocks GPCR internalization through inhibition of ARF6.
  • Treatment results in a dose-dependent reduction in MDA-MB-231 cells.
  • Inhibits the recruitment of the clathrin adaptor AP-2 to β-arrestin2 and receptor internalization, both processes that require active ARF6.

Catalog No. 50-003-50838


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