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ABclonal Technology RbAp46/RBBP7 Rabbit mAb
Supplier: ABclonal Technology A22274100UL
This protein is a ubiquitously expressed nuclear protein and belongs to a highly conserved subfamily of WD-repeat proteins It is found among several proteins that binds directly to retinoblastoma protein which regulates cell proliferation The encoded protein is found in many histone deacetylase complexes including mSin3 co-repressor complex It is also present in protein complexes involved in chromatin assembly This protein can interact with BRCA1 tumor-suppressor gene and may have a role in the regulation of cell proliferation and differentiation Two transcript variants encoding different isoforms have been found for this gene
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