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AdipoGen Rebeccamycin
Supplier: AdipoGen BVT0139M001
Chemical. CAS 93908-02-2. Formula C27H21Cl2N3O7. MW 570.4. Isolated from Streptomyces sp. Antibiotic. Weak topoisomerase I Topo I inhibitor. Structurally similar to staurosporine. Does not show any inhibitory activity against protein kinases. Shows significant antitumor properties in vitro IC50 = 480 nM against mouse B16 melanoma cells and IC50 = 500 nM against P388 leukemia cells.
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