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Selleck Chemical LLC Resatorvid
Supplier: Selleck Chemical LLC S7455100MG
Resatorvid (TAK-242 CLI-095) is a small-molecule-specific inhibitor of Toll-like receptor (TLR) 4 signaling blocking LPS-induced production of NO TNF- and IL-6 in macrophages with IC50 of 1 8 nM 1 9 nM and 1 3 nM respectively Resatorvid downregulates expression of TLR4 downstream signaling molecules MyD88 and TRIF Resatorvid inhibits autophagy
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