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Apexbio Technology LLC Reserpine hydrochloride 16994-56-2 10mM (in 1mL DMSO)
Supplier: Apexbio Technology LLC B12705.1
Reserpine hydrochloride (CAS 16994-56-2) is a small-molecule inhibitor targeting vesicular monoamine transporter (VMAT) particularly VMAT2 It is designed to inhibit monoaminergic neurotransmitter storage and transport thereby regulating synaptic transmission dynamics Reserpine hydrochloride exerts its biological activity primarily through irreversible binding and blockade of VMAT resulting in the depletion of monoamine neurotransmitters including dopamine norepinephrine and serotonin within neuronal vesicles In biochemical assays reserpine hydrochloride demonstrates inhibitory activity against VMAT2 with an IC50 value typically around 34 nM Based on these pharmacological properties reserpine hydrochloride holds research potential in neuropharmacological studies investigating monoamine signaling pathways synaptic transmission and psychiatric disorder models
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