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Medchemexpress LLC Resminostat hydrochloride | 1187075-34-8 | 99.7% | 385.87 | 50 MG
SDP

Supplier:  Medchemexpress LLC HY14718A50MG

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Resminostat hydrochloride is a potent inhibitor of HDAC1, HDAC3, and HDAC6 (IC50 values: 42.5, 50.1, 71.8 nM, respectively), and a less potent inhibitor of HDAC8 (IC50: 877 nM). It is for research use only.

  • Induces histone acetylation and inhibits myeloma cell growth.
  • Displays substrate competitive binding (Ki: 27 nM).
  • Modulates bcl-2 proteins and inhibits Akt pathway signalling.
  • Synergistic with other anti-myeloma agents.
  • Inhibits HNSCC cell growth (IC50s: 0.775-1.572 μM).
  • Synergistic effect with irradiation on HNSCC cells.
  • Reduces HCC cell viability with AZD-2014 co-treatment.

Catalog No. 50-003-59846


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