Medchemexpress LLC Reverse transcriptase-IN-1 | 2380001-43-2 | 98.1% | 100 MG

Supplier:  Medchemexpress LLC HY130241100MG

Reverse transcriptase-IN-1 (Compound 12z) is a potent, orally active HIV-1 nonnucleoside reverse transcriptase inhibitor. It demonstrates antiviral activity against HIV-1 IIIB, E138K, and K103N mutants, with EC50 values of 3.4 nM, 4.3 nM, and 3.6 nM respectively. It also exhibits an IC50 of 13.7 nM against the HIV-1 reverse transcriptase enzyme. Studies indicate significantly improved oral bioavailability and potential as an orally bioavailable candidate for human HIV-1 infection research.

• Potent, orally active HIV-1 nonnucleoside reverse transcriptase inhibitor
• Demonstrates antiviral activity against various HIV-1 mutants
• Exhibits IC50 of 13.7 nM against HIV-1 reverse transcriptase enzyme
• Improved oral bioavailability
• Potential candidate for human HIV-1 infection research

Catalog No. 50-003-38193