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Medchemexpress LLC Rimantadine hydrochloride | 1501-84-4 | 98.0% | 1 G
Supplier: Medchemexpress LLC HYB0338A1G
Rimantadine hydrochloride (Flumadine hydrochloride) is an orally active inhibitor for M2 protein that blocks hydrogen ion channel activity, preventing virus entry and replication. It exhibits broad-spectrum antiviral activity. It is for research use only and not sold to patients.
- Inhibits RNA levels of hepatitis A virus (HAV) in Huh7 and IHH cells with IC50 values of 6.7 and 1.6 μg/mL
- Increases expression of the autophagy marker LC3 and promotes autophagy in HAV-infected Huh7 cells
- Exhibits anti-infectious activity when combined with Oseltamivir in H3N2-infected mouse models
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