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Medchemexpress LLC Rimcazole (dihydrochloride) | 75859-03-9 | 99.9% | 394.38 | 10 MM * 1 ML
Supplier: Medchemexpress LLC HY10851010MG
Rimcazole (BW 234U) dihydrochloride is a carbazole derivative that acts in part as a sigma (σ) receptor antagonist. It also binds with moderate affinity to the dopamine transporter and inhibits dopamine uptake. Rimcazole dihydrochloride can reduce locomotor activity and sensitization and can be used for cancer research.
- Sigma (σ) receptor antagonist.
- Binds with moderate affinity to the dopamine transporter.
- Inhibits dopamine uptake.
- Can reduce locomotor activity and sensitization.
- Can be used for the research of cancer.
- Induces a transient accumulation of HIF-1α protein in cancer cells (HCT-116p53+/+ and MDA MB 231 cells) but not in normal human dermal fibroblasts.
- Concentration-dependently decreases the number of HCT-116p53+/+ cells.
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