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Medchemexpress LLC Rimonabant | 168273-06-1 | 99.5% | C22H21Cl3N4O | 50 MG
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Supplier:  Medchemexpress LLC HY14171650MG

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Rimonabant (SR141716) is a highly potent, brain-penetrated, and selective central cannabinoid receptor (CB1) antagonist with a Ki of 1.8 nM. It also inhibits Mycobacterial membrane protein Large 3 (MMPL3).

  • Highly potent, brain-penetrated, and selective central cannabinoid receptor (CB1) antagonist
  • Inhibits mycobacterial membrane protein Large 3 (MMPL3)
  • Exhibits Ki of 1.8 nM for CB1
  • Inhibits LPS-induced NO production in BV-2 cells (IC50 = 16.17 μM)
  • Can inhibit the growth of Mtb with an MIC of 54 μM
  • Reduced RANTES and MCP-1 serum levels in obese Zucker rats
  • Slowed weight gain and reduced platelet-bound fibrinogen in obese Zucker rats
  • Significantly reduced many cardiometabolic risk factors

Catalog No. 50-003-53986


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