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Medchemexpress LLC RIP1 kinase inhibitor 1 | 2095515-38-9 | 99.96% | 461.90 | 10 MG
Supplier: Medchemexpress LLC 10MGHY111409
RIP1 kinase inhibitor 1 (compound 22) is a highly potent, orally available, and brain-penetrating RIP1 kinase inhibitor with a pKi of 9.04. It strongly suppresses necroptotic cell death and phosphorylation of MLKL in human colorectal adenocarcinoma HT-29 cells and mouse L-cells NCTC 929.
- Highly potent and orally available
- Brain-penetrating RIP1 kinase inhibitor
- Suppresses necroptotic cell death
- Inhibits phosphorylation of MLKL
- Effective in human colorectal adenocarcinoma HT-29 cells
- Effective in mouse L-cells NCTC 929
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