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New England Biolabs, Inc. RNase Inhibitor, Murine (Glycerol-free) – 3000 units
SDP

Supplier:  New England Biolabs, Inc. M0628S

Encompass

RNase Inhibitor, Murine (Glycerol-free) is a 50 kDa recombinant protein of murine origin. The inhibitor specifically inhibits RNases A, B and C by binding noncovalently in a 1:1 ratio with high affinity. It is not effective against RNase 1, RNase T1, S1 Nuclease, RNase H or RNase from Aspergillus. In addition, no inhibition of polymerase activity is observed when RNase Inhibitor is used with Taq DNA Polymerase, AMV or M-MuLV Reverse Transcriptases, or Phage RNA Polymerases (SP6, T7, or T3).    Recombinant murine RNase inhibitor lacks the cysteines identified in the human version to be sensitive to oxidation, which causes inactivation of the inhibitor. As a result, RNase Inhibitor, Murine has significantly improved resistance to oxidation compared to the human/porcine RNase inhibitors, and is stable at low reducing agent concentrations (≤ 1 mM). This makes it ideal for reactions where low concentration reducing agent is required (e.g. Real-time RT-PCR).

Catalog No. 50-004-60444


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