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Abcam Ro 25-6981 maleate salt (mM/ml), NR2B antagonist, 20MM_ML
Supplier: Abcam AB14669520MM_ML
MW 455.5 Da, Purity >98%. Potent, highly selective, activity-dependent blocker of NMDA receptors that contain the NR2B subunit (IC₅₀ values are 0.009 and 52 μM at NR1C/NR2B and NR1C/NR2A, respectively). Displays no significant activity at kainate/AMPA receptors, Na+ and Ca²+ channels at concentrations showing maximal protection in neurotoxicity tests. Neuroprotective actions in vivo and in vitro.
The product is subject to the following: Abcam Restricted Use Statement
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