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Medchemexpress LLC Ro 90-7501 | 293762-45-5 | 99.1% | 340.38 g/mol | C20H16N6 | 10 MG
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Supplier:  Medchemexpress LLC HY10324110MG

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Ro 90-7501 is a small-molecule research compound that inhibits amyloid β42 (Aβ42) fibril assembly and reduces Aβ42-induced cytotoxicity (EC50 2 μM). It also modulates protein phosphatase activity and DNA damage response pathways, enhances innate antiviral signaling, and has demonstrated radiosensitizing effects in cell models.

  • Inhibits amyloid β42 fibril assembly and reduces Aβ42 cytotoxicity (EC50 2 μM).
  • Inhibits protein phosphatase 5 and modulates ATM phosphorylation and DNA repair.
  • Enhances TLR3 and RIG-I-like receptor-mediated IFN-β expression.
  • Shows radiosensitizing effects in cancer cell models.
  • High purity (99.1%) and characterized molecular weight (340.38 g/mol).
  • Soluble in DMSO (≈41.67 mg/mL) with recommended storage for powder and solutions.

Catalog No. 50-002-47482


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