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Medchemexpress LLC Romaciclib monohydrochloride | 2443816-41-7 | 99.3% | 450.60 | 50 MG
SDP

Supplier:  Medchemexpress LLC HY111388A100MG

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Romaciclib monohydrochloride is an ATP-competitive and selective CDK8 inhibitor, inhibiting kinase activities of CDK8/CycC and CDK19/CycC complexes. It weakly inhibits CDK9 but shows no obvious activity against CDK1, 2, 4, 6, 5, 7. This compound inhibits phosphorylation of STAT1 S727 and STAT5 S726 and has anti-tumor activity. It is for research use only.

  • Inhibits kinase activities of CDK8/CycC and CDK19/CycC complexes.
  • Weakly inhibits CDK9.
  • Shows no obvious activity against CDK1, 2, 4, 6, 5, 7.
  • Inhibits phosphorylation of STAT1 S727 and STAT5 S726.
  • Has anti-tumor activity.

Catalog No. 50-003-46477


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