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Selleck Chemical LLC Ropsacitinib S9676-100MG

Supplier: Selleck Chemical LLC S9676100MG
Ropsacitinib (PF-06826647 Tyk2-IN-8 compound 10) is a selective and orally administered inhibitor of tyrosine kinase 2 (TYK2) with IC50 of 17 nM for binding to TYK2 catalytically active JH1 domain PF-06826647 (Tyk2-IN-8 compound 10) also inhibits JAK1 and JAK2 with IC50 of 383 nM and 74 nM respectively PF-06826647 (Tyk2-IN-8 compound 10) is used in the treatment of psoriasis (PSO)
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